senescence

Extensive mechanical tension promotes annulus fibrosus cell senescence through suppressing cellular autophagy
Liang Zhao, Baofang Tian, Qing Xu, Cunxin Zhang, Luo Zhang, Haolin Fang

Bioscience Reports Apr 2019, 39 (4) BSR20190163; DOI: 10.1042/BSR20190163
The resistant effect of SIRT1 in oxidative stress-induced senescence of rat nucleus pulposus cell is regulated by Akt-FoxO1 pathway
Junsheng He, Ailiang Zhang, Zhiwen Song, Shiwu Guo, Yuwei Chen, Zhiyuan Liu, Jinlong Zhang, Xu Xu, Jinbo Liu, Lei Chu

Bioscience Reports Apr 2019, BSR20190112; DOI: 10.1042/BSR20190112
Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells
Zhenhua Fei, Wei Gao, Raoying Xie, Ganzhu Feng, Xiaolin Chen, Yiyan Jiang

Bioscience Reports Feb 2019, 39 (2) BSR20181298; DOI: 10.1042/BSR20181298
Acidic pH promotes nucleus pulposus cell senescence through activating the p38 MAPK pathway
Jiabin Fu, Wei Yu, Dianming Jiang

Bioscience Reports Dec 2018, 38 (6) BSR20181451; DOI: 10.1042/BSR20181451
Resveratrol attenuates high glucose-induced nucleus pulposus cell apoptosis and senescence through activating the ROS-mediated PI3K/Akt pathway
Wenping Wang, Pei Li, Jiagang Xu, Xiangkun Wu, Zhiliang Guo, Lijing Fan, Ruipeng Song, Jianli Wang, Li Wei, Haijun Teng

Bioscience Reports Apr 2018, 38 (2) BSR20171454; DOI: 10.1042/BSR20171454
The response of nucleus pulposus cell senescence to static and dynamic compressions in a disc organ culture
Jianmin Shi, Lianglong Pang, Shouguo Jiao

Bioscience Reports Apr 2018, 38 (2) BSR20180064; DOI: 10.1042/BSR20180064
Role of p38–MAPK pathway in the effects of high-magnitude compression on nucleus pulposus cell senescence in a disc perfusion culture
Lianglong Pang, Pei Li, Ruijie Zhang, Yuan Xu, Lei Song, Qiang Zhou

Bioscience Reports Oct 2017, 37 (5) BSR20170718; DOI: 10.1042/BSR20170718
MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells
Lijs Beke, Cenk Kig, Joannes T. M. Linders, Shannah Boens, An Boeckx, Erika van Heerde, Marc Parade, An De Bondt, Ilse Van den Wyngaert, Tarig Bashir, Souichi Ogata, Lieven Meerpoel, Aleyde Van Eynde, Christopher N. Johnson, Monique Beullens, Dirk Brehmer, Mathieu Bollen

Bioscience Reports Dec 2015, 35 (6) e00267; DOI: 10.1042/BSR20150194
Re-expression of HPV16 E2 in SiHa (human cervical cancer) cells potentiates NF-κB activation induced by TNF-α concurrently increasing senescence and survival
Devan Prabhavathy, Chandrasekaran Karthik Subramanian, Devarajan Karunagaran

Bioscience Reports Feb 2015, 35 (1) e00175; DOI: 10.1042/BSR20140160
Molecular interactions of Bcl-2 and Bcl-xL with mortalin: identification and functional characterization
Nishant Saxena, Shashank P. Katiyar, Ye Liu, Abhinav Grover, Ran Gao, Durai Sundar, Sunil C. Kaul, Renu Wadhwa

Bioscience Reports Oct 2013, 33 (5) e00073; DOI: 10.1042/BSR20130034

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