Table 3 Equilibrium denaturation by guanidine
CXCL8 mutantTransition midpoint (M) guanidine
wtCXCL84.96±0.1
CXCL8(Δ6F17RF21RE70K)2.15±3.6
CXCL8(Δ6F17RF21RN71K)1.76±0.47
CXCL8(Δ6F17RF21RE70KN71R)4.51±0.12
CXCL8(Δ6F17RF21RE70RN71K)3.89±0.26
CXCL8(Δ6F17KF21KE70KN71K)4.1±0.13