Table 1

The characteristics of included studies

First author, yearCountryEthnicityType of diseaseSample sizeGenotype distributionP-value for HWENOS score
CasesControls
LEPR rs1137100AA/AG/GG
Aijälä, 2014 [16]FinlandCaucasianCAD151/87766/75/10361/398/1180.6177
An, 2016 [17]ChinaEast AsianCAD421/550295/110/16371/157/220.2997
Roszkowska-Gancarz, 2014 [20]RussiaCaucasianMI226/414118/86/22218/171/250.2597
LEPR rs1137101GG/GA/AA
Aijälä, 2014 [16]FinlandCaucasianCAD152/88248/80/24312/427/1430.8787
An, 2016 [17]ChinaEast AsianCAD421/550306/103/12362/162/260.1587
Khaki-Khatibi, 2018 [18]IranSouth AsianMI80/8018/37/2530/36/140.5768
Nowzari, 2018 [19]IranSouth AsianCAD156/13070/61/2563/34/33<0.0017
Roszkowska-Gancarz, 2014 [20]RussiaCaucasianMI226/41459/108/59116/206/920.9767
Wu, 2013 [22]ChinaEast AsianCAD200/10042/90/6844/38/180.0648
LEP rs7799039GG/GA/AA
Nowzari, 2018 [19]IranSouth AsianCAD156/13061/73/2258/51/210.0957
Roszkowska-Gancarz, 2014 [20]RussiaCaucasianMI226/41467/120/39139/203/720.8857
Wang, 2013 [21]ChinaEast AsianCAD200/10065/100/3537/46/170.6778
Zhai, 2013 [23]ChinaEast AsianCAD200/100102/86/1245/38/170.0808
Zhao, 2006 [24]ChinaEast AsianCAD156/15080/68/868/56/260.0208
Zheng, 2014 [25]ChinaEast AsianCAD198/9568/97/3365/24/60.0847
  • Abbreviation: MI, myocardial infarction.