Table 1 Erythrogram after adminstration of gentamicin and the protective role of Carica papaya leaf extract
ParametersGroups
CDSTSDTLD
RBC (1012/l)7.87 ± 0.274.97 ± 0.2917.17 ± 0.3526.78 ± 0.2127.10 ± 0.272
PCV (%)46.73 ± 2.4328.33 ± 3.75141.87 ± 2.74238.67 ± 2.61241.34 ± 3.202
HGB (g/dl)14.07 ± 1.597.73 ± 0.72113.02 ± 0.95211.61 ± 0.93212.83 ± 0.912
MCV (fl)59.81 ± 2.9357.03 ± 2.3158.73 ± 2.3557.14 ± 2.0358.13 ± 2.17
MCH (pg)18.21 ± 1.4815.61 ± 1.2818.03 ± 1.2717.23 ± 1.1817.84 ± 1.27
MCHC (g/dl)30.47 ± 2.1127.11 ± 1.7530.68 ± 1.8730.05 ± 2.0730.85 ± 1.86
  • C: Control (saline was orally adminstered for 21 consecutive days); D: Diseased (gentamicin was s.c injected at dosage of 100 mg/kg b wt., for 21 consecutive days); TSD or TLD: Treated with small or large dose (Carica papaya leaf extract was orally administered at dosage of 150 or 300 mg/kg b wt., for 21 consecutive days); S: Standard (Ferrous ascorbate + Folate as a combination of 13.5 + 0.135 mg/kg b wt. was orally administered for 21 consecutive days); Data are presented as Mean ± SE (n=6); 1 and 2 mean significantly (P<0.05) different from Normal and Diseased, respectively.