Table 2 Leukogram after adminstration of gentamicin and the protective role of Carica papaya leaf extract
ParametersGroups
CDSTSDTLD
WBC (109/l)14.63 ± 1.6325.43 ± 2.43116.96 ± 1.09218.13 ± 1.20217.20 ± 1.362
Lymph. (%)72.93 ± 3.4169.33 ± 3.7572.46 ± 3.0771.06 ± 2.3972.27 ± 3.58
Mid-sized (%)2.43 ± 0.611.79 ± 0.272.24 ± 0.412.07 ± 0.302.72 ± 0.29
Granulocytes (%)24.36 ± 0.8829.18 ± 1.59125.16 ± 1.74226.30 ± 1.46225.17 ± 1.172
PLT (109/l)562.7 ± 7.84481.67 ± 10.21546.3 ± 25.8623.2 ± 39.22720.7 ± 52.92
  • C: Control (saline was orally adminstered for 21 consecutive days); D: Diseased (gentamicin was s.c injected at dosage of 100 mg/kg b wt., for 21 consecutive days); TSD or TLD: Treated with small or large dose (Carica papaya leaf extract was orally administered at dosage of 150 or 300 mg/kg b wt., for 21 consecutive days); S: Standard (Ferrous ascorbate + Folate as a combination of 13.5 + 0.135 mg/kg b wt. was orally administered for 21 consecutive days); Data are presented as Mean ± SE (n=6); 1 and 2 mean significantly (P<0.05) different from Normal and Diseased, respectively.