Table 4 Comparison of genotypic and allelic frequencies of GDF5/rs143383 polymorphism amongst KOA subgroups stratified
CasesTTCTCCTC
ESR ≥ 2074 (48.4)49 (32.0)30 (19.6)197 (64.4)109 (35.6)
ESR < 2050 (37.0)56 (41.5)29 (21.5)156 (57.8)114 (42.2)
P0.2610.0500.105
OR (95% CI)0.70 (0.38–1.30)0.59 (0.35–1.20)1.000.76 (0.54–1.06)1.00
CRP > 8 mg/l83 (44.9)68 (36.8)34 (18.4)234 (63.2)136 (36.7)
CRP ≤ 8 mg/l41 (39.8)37 (35.9)25 (24.3)119 (57.8)87 (42.2)
P0.6720.9080.196
OR (95% CI)0.67 (0.35–1.27)0.91 (0.53–1.57)1.000.79 (0.56–1.13)1.00
Grade I/II64 (41.3)61 (39.4)30 (19.4)189 (38.3)121 (61.7)
Grade III/IV60 (45.1)44 (33.1)29 (21.8)164 (43.1)102 (56.9)
P0.3270.9230.866
OR (95%CI)0.77 (0.46–1.30)1.03 (0.56–1.92)1.001.03 (0.74–1.44)1.00