Table 2 The general information of OPRM1 and ABCB1 SNPs in 225 patients underwent radical section of lung cancer
SNPsGenotypePatients (n)Age (years)Sex (men/women)BMI (kg/m2)ASA score (I/II)PPT (g)SAI (low/high)
OPRM1 rs1799971AA11552.35 ± 10.5568/4222.43 ± 3.1661/4196.85 ± 52.0195/20
AG7851.98 ± 11.2444/3422.98 ± 2.9442/3199.75 ± 49.8771/7
GG3253.30 ± 12.4520/1723.04 ± 3.1229/2194.86 ± 50.6129/3
OPRM1 rs563649AA10453.15 ± 11.7661/4322.86 ± 2.8558/3992.94 ± 57.4385/19
AG7851.43 ± 12.3443/3523.14 ± 3.0243/3698.54 ± 49.8565/13
GG4352.43 ± 12.0428/1522.54 ± 2.4631/1896.87 ± 52.3636/7
OPRM1 rs1323040CC12451.45 ± 13.0171/5023.14 ± 2.7567/4893.45 ± 53.24103/21
CT7952.51 ± 12.3442/3422.86 ± 3.1041/3197.52 ± 54.2567/12
TT2253.09 ± 12.1419/923.05 ± 3.1424/14105.24 ± 58.9816/6
ABCB1 rs2032582GG10953.06 ± 11.8565/4422.65 ± 3.2461/4095.64 ± 49.6891/18
GA8552.49 ± 12.4249/3623.10 ± 3.1647/3596.54 ± 52.1474/11
AA3152.41 ± 11.9718/1322.56 ± 2.9824/1894.38 ± 53.6424/7
ABCB1 rs1045642CC12053.08 ± 12.4569/4823.08 ± 3.2468/4996.52 ± 41.6597/23
CT5852.14 ± 11.3535/2622.64 ± 2.9837/2594.52 ± 46.5447/11
TT4751.78 ± 12.0428/1922.89 ± 3.0627/1996.54 ± 50.2438/9
ABCB1 rs1128503CC13152.45 ± 11.3874/5623.14 ± 3.2472/5495.84 ± 48.75105/26
CT6353.64 ± 12.3439/2522.99 ± 2.9840/2697.84 ± 53.2150/13
TT3151.79 ± 13.0619/1223.07 ± 3.2420/13101.52 ± 53.2427/4
  • Note: *P<0.05, compared with wide-type homozygotes; ASA, American Society of Anesthesiologists; BMI, body mass index, PPT, pressure pain threshold, SAI, state anxiety index.