Table 4 Summary of the side effects of different genotype groups
SNPsGenotypePatients (n)Nausea (%)Vomiting (%)Respiratory depression (%)Pruritus (%)
OPRM1 rs1799971AA1154 (3.48%)3 (2.61%)2 (1.74%)1 (0.87%)
AG782 (2.56%)1 (1.28%)1 (1.28%)1 (1.28%)
GG321 (3.13%)0 (0)0 (0)0 (0)
OPRM1 rs563649AA1043 (2.88%)3 (2.88%)2 (1.92%)2 (1.92%)
AG782 (2.56%)1 (1.28%)0 (0)0 (0)
GG432 (4.56%)0 (0)1 (2.33%)0 (0)
OPRM1 rs1323040CC1245 (4.03%)4 (3.23%)3 (2.42%)2 (1.61%)
CT793 (3.80%)0 (0)0 (0)0 (0)
TT220 (0)0 (0)0 (0)0 (0)
ABCB1 rs2032582GG1094 (3.67%)4 (3.67%)2 (1.8%)1 (0.92%)
GT853 (3.53%)0 (0)1 (1.18%)0 (0)
TT310 (0)0 (0)0 (0)1 (3.23%)
ABCB1 rs1045642CC1204 (3.33%)3 (2.50%)3 (2.50%)2 (1.67%)
CT582 (3.45%)0 (0)0 (0)0 (0)
TT471 (2.13%)1 (2.13%)0 (0)0 (0)
ABCB1 rs1128503CC1315 (3.82%)4 (3.05%)2 (1.53%)1 (0.76%)
CT632 (3.17%)0 (0)1 (1.59%)1 (1.59%)
TT310 (0)0 (0)0 (0)0 (0)