Table 2 The association of lncRNA polymorphisms and hepatocellular risk stratified by host characteristics
VariablesGenotypeHCC compared with CONPOR (95% CI)
H19 rs2735971
Gender
MaleGG276/2481 (Ref.)
AG93/1170.0480.72 (0.52–1.00)
AA9/90.7910.88 (0.34–2.26)
FemaleGG51/651 (Ref.)
AG33/220.0581.92 (0.98–3.78)
AA3/40.8040.82 (0.17–4.05)
Age
≤60GG205/2301 (Ref.)
AG87/1020.8110.96 (0.68–1.35)
AA8/70.5371.35 (0.48–3.81)
>60GG122/831 (Ref.)
AG39/370.1600.68 (0.40–1.17)
AA4/60.2160.44 (0.12–1.62)
Smoking
Ever smokerGG56/801 (Ref.)
AG19/430.1050.58 (0.30–1.12)
AA3/40.9521.05 (0.23–4.89)
Never smokedGG152/1281 (Ref.)
AG62/620.3570.81 (0.53–1.26)
AA7/60.8861.09 (0.33–3.63)
Alcohol drinking
DrinkerGG32/571 (Ref.)
AG11/330.1710.57 (0.25–1.28)
AA3/10.1575.39 (0.52–55.55)
Non-drinkerGG175/1511 (Ref.)
AG70/710.4130.84 (0.56–1.27)
AA7/90.4850.68 (0.24–1.98)
H19 rs2839698
Gender
MaleCC176/1951 (Ref.)
CT168/1520.1911.22 (0.91–1.65)
TT33/240.1471.52 (0.86–2.68)
FemaleCC39/501 (Ref.)
CT43/330.0921.74 (0.91–3.30)
TT7/80.7291.23 (0.39–3.91)
Age
≤60CC135/1851 (Ref.)
CT143/1250.0071.57 (1.13–2.18)
TT25/250.2761.40 (0.78–2.55)
>60CC80/601 (Ref.)
CT68/600.5280.86 (0.53–1.39)
TT15/70.3201.63 (0.62–4.27)
Smoking
Ever smokerCC29/651 (Ref.)
CT40/500.0411.89 (1.03–3.48)
TT9/100.1552.08(0.76–5.68)
Never smokedCC112/1051 (Ref.)
CT88/780.9171.02 (0.67–1.55)
TT22/120.1211.88 (0.85–4.16)
Alcohol drinking
DrinkerCC19/451 (Ref.)
CT22/400.4021.39 (0.65–2.97)
TT5/40.0883.68 (0.82–16.46)
Non-drinkerCC121/1241 (Ref.)
CT106/880.3601.20 (0.81–1.76)
TT26/180.1661.61 (0.82–3.15)
H19 rs3024270
Gender
MaleGG129/1361 (Ref.)
CG181/1730.5731.10 (0.80–1.51)
CC71/640.4521.17 (0.77–1.78)
FemaleGG22/341 (Ref.)
CG44/420.0921.86 (0.90–3.82)
CC24/170.0512.39 (1.00–5.73)
Age
≤60GG93/1281 (Ref.)
CG145/1570.1531.40 (0.88–2.21)
CC67/560.0191.71 (1.09–2.68)
>60GG58/421 (Ref.)
CG80/580.1511.29 (0.91–1.84)
CC28/250.4380.76 (0.39–1.51)
Smoking
Ever smokerGG17/441 (Ref.)
CG44/570.0551.96 (0.99–3.89)
CC18/240.1221.93 (0.84–4.42)
Never smokedGG74/691 (Ref.)
CG100/940.8020.94 (0.60–1.48)
CC50/360.3101.34 (0.76–2.34)
Alcohol drinking
DrinkerGG13/261 (Ref.)
CG23/480.9210.96 (0.41–2.22)
CC10/160.5531.37 (0.48–3.93)
Non-drinkerGG77/871 (Ref.)
CG121/1020.1861.33 (0.87–2.01)
CC58/440.0991.53 (0.92–2.55)
  • Abbreviation: CI, confidence interval. The bold text means the significant results.