Table 2 Micro-CT analysis of cancellous bone of the femur
Sham (n=8)OVX (n=8)E2 (n=8)E2 + G15 (n=8)
BMC (mg)6.24±0.382.79±0.215.01±0.27*5.54±0.26*#
BMD (mg/mL)579±40395±25506±28*552±23*#
BV/TV0.65±0.050.31±0.040.45±0.03*0.57±0.05*#
Tb.Th. (mm)0.110±0.0110.065±0.0070.088±0.008*0.104±0.009*#
Tb.Sp. (mm)0.065±0.0070.161±0.0120.105±0.010*0.91±0.008*#
CD (1/mm3)85.13±6.2073.69±5.7380.44±6.00*82.80±5.53*
  • Sham/OVX: olive oil, 1.5 ml/kg, ip, three times/week; E2: 35 μg/kg, ip, three times/week; G15: 160 μg/kg, ip, three times/week; all for 6 weeks. *P<0.05 compared with OVX; # P<0.05 compared with E2.