Table 1 Effects of combination therapy of E2 with G15 on biochemical parameters in the serum of OVX rats
Sham (n=8)OVX (n=8)E2 (n=8)E2 + G15 (n=8)
Ca (mmol/l)2.81±0.222.60±0.232.78±0.192.79±0.24
P (mmol/l)1.76±0.171.70±0.211.75±0.151.74±0.16
ALP (unit/l)124±16246±21144±16*134±19*
OC (ng/ml)4.38±0.234.82±0.284.55±0.18*4.49±0.20*
TRACP (pg/l)2808±1233243±1322950±135*2869±123*
CTX-(ng/ml)432±22587±20492±19*464±20*#
  • Sham/OVX: olive oil, 1.5 ml/kg, ip, three times/week; E2: 35 μg/kg, ip, three times/week; G15: 160 μg/kg, ip, three times/week; all for 6 weeks. *P<0.05 compared with OVX; # P<0.05 compared with E2.