This meta-analysis was performed to evaluate the effect of cognitive behavioral therapy (CBT) in improving the depression symptoms of patients with diabetes. Literature search was conducted in PubMed and Embase up to Oct 2016 without initial date. The pooled SMD (standard mean difference) and its 95% confidence interval (CI) were calculated by Revman 5.3. Subgroup analyses were performed by type of diabetes and evaluation criteria of depression. A total of 5 randomized control trials involving 834 patients with diabetes mellitus (including 417 patients in CBT group and 417 patients in control group) were included in this meta-analysis. The pooled estimates indicated significant improvement of depression by CBT compared with routine approaches in overall outcomes (SMD = -0.33, 95% CI = -0.46 to -0.21, P < 0.00001), post-intervention outcomes (SMD = -0.43, 95% CI = -0.73 to -0.12, P = 0.006) and outcomes after 12 months intervention (SMD = -0.38, 95% CI = -0.54 to -0.23, P < 0.0001). Subgroup analyses showed that the results were not influenced by the type of diabetes. However, the effect of CBT on improving the depression symptoms was disappeared when only using CES-D (Centre for Epidemiological Studies scale for Depression) to evaluate depression.
- cognitive behavioral therapy
- depression, diabetes
- meta analysis
- ©2017 The Author(s)
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